Lipoprotein Lipase Deficiency (LPLD)
Lipoprotein lipase deficiency (sometimes called familial lipoprotein lipase deficiency or chylomicronaemia, and usually shortened to LPLD, is a rare genetic disorder that affects one person in a million.
People with LPLD have very high triglyceride levels because they lack lipase, the enzyme that clears triglycerides (a kind of fat) from the blood. Raised triglycerides are present from childhood but the condition may not be diagnosed until adulthood.
Symptoms include recurrent abdominal pain, fat-filled spots known as ‘eruptive xanthomata’, and attacks of acute pancreatitis.
Most medications have only modest benefits, although new ones are being developed. The main treatment is by diet, which must be as low in fat as possible.
Find out about Jill, who was diagnosed with LPLD when she was just 2 years old.
Check out HEART UK's Low Fat Eating Plan