FH - The Challenge to Find and Treat - View a series of podcasts on familial hypercholesterolemia from the BJC. Register here to view more podcasts from the BJC.
Watch this film to hear GP, Dr Sarah Jarvis, and patients, talk about inherited high cholesterol
To hear how HEART UK can help you view our movie “About HEART UK”.
Temme EHM, Mensink RP, Hornstra G (1996) Comparison of the effects of diets enriched with lauric, palmitic or oleic acids on serum lipids and lipoproteins in healthy men and women. Am J Clin Nutr 1996; 63: 897-903.
Cardiovascular Disease and risk factors:
Salim Yusuf, Steven Hawken, Stephanie Ôunpuu, Tony Dans, Alvaro Avezum, Fernando Lanas, Matthew McQueen, Andrzej Budaj, Prem Pais, John Varigos, Liu Lisheng, on behalf of the INTERHEART Study Investigators* Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study Lancet 2004; 364: 937–52
PCCJ sponsored Familial Hypercholesterolaemia Series
For free access to these articles, you can sign up to the PCCJ Plus Website at www.pccj.eu
Milne D (2013) Its not just a high cholesterol, it can be an indicator of a genetic disorder. Prim Care Cardiovasc Journal. 6. pp122-124.
Neely, R (2013). The importance of early diagnosis: how to identify patients with FH for diagnosis and referral. Prim Care Cardiovasc Journal. 7. 1. pp31-35
Thompson, G. and Seed, M (2014) The management of familial hypercholesterolaemia. Prim Care Cardiovasc Journal. 7 pp89-91
Humphries, S. and Futema, M. (2015) What's new in FH genetics? Prim Care Cardiovasc Journal. 1. 1. Epublication online
Statins and Treatments:
Cholesterol Treatment Trialists (CTT) Collaborators. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 2010. vol 376, no 9753. 1670-1680
Cholesterol Treatment Trialists (CTT) Collaborators. The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease. Meta analysis of individual data from 27 randomised trials. Lancet 2012. Aug 11, 380 (9841) 581-590
Cannon CP. IMPROVE-IT Trial. A comparison of Ezetimibe/Simvastatin versus Simvastatin monotherapy on cardiovascular outcomes after acute coronary syndromes. Presented at: American Heart Association Scientific Sessions, 17 November 2014, Chicago, USA
Finegold JA, Manisty CH, Goldacre B, Barron AJ, Francis DP. What proportion of symptomatic side effects in patients taking statins are genuinely caused by the drug? Systematic review of randomised placebo controlled trials to aid individual patient choice. European Journal of Preventative Cardiology. 2014, 21: 464
Thompson G (2008) The Cholesterol Controversy. Royal Society of Medicine Press Ltd, London
LDL Apheresis and Plasma Exchange: (29 references)
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