FH medway report
Finding FH in GP practices Medway

80-90% of Familial Hypercholesterolemia​ (FH) cases remain undiagnosed. Two simple interventions improved diagnosis of genetic inherited high cholesterol in one CCG. Could your CCG establish a similar Familial Hypercholesterolemia programme? 

Simon Broome Register

Providing a resource for research. The aims are to improve diagnosis and treatment and prevent early heart disease.
Governance and contacts
The history
Key findings
DNA testing in FH
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Apheresis in HoFH
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Risk calculators

Health professionals commonly use risk calculators to assess the 10 year cardiovascular risk of patients to help them identifying the need for lifestyle change and medication.*

*Risk calculators should not be used for people already identified as at high risk such as those with diabetes or FH.

Cardiovascular risk scores
Risk calculators generate a “score” which estimates the probability of cardiovascular disease in individuals who have not already developed major atherosclerotic disease. These scores aid decision making in clinical practice and guide the type of interventions that doctors and other health care professioanls advise and prescribe.

Risk Calculators have been developed based on the following:

Until recently, NICE recomended this equation for calculating cardiovascular risk.

Joint British Societies (JBS)
The official cardiovascular risk charts published in the British National Formulary (BNF) are based on those given in the JBS2 guidelines.

The Joint British Societies' consensus recommendations for the prevention of cardiovascular disease (JBS3) are now available and refer to lifetime risk as well as 10 year risk.  The calculator can be downloaded at the following link: www.jbs3risk.com

Developed for use in Scottish populations ASSIGN includes risk factors, such as family history and social deprivation, not used by Framingham.

This risk algorithm has been developed by doctors and academics working in the UK and is based on routinely collected data from many thousands of GPs across the country. A version using lifetime risk is available at www.qrisk.org