LDL Apheresis Toolkit

HEART UK Lipoprotein Apheresis Toolkit

A toolkit to inform clinicians, patients and commissioners about lipoprotein apheresis treatment.

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LDL-apheresis referral
LDL-apheresis referral

If you think you may need to have apheresis treatment, talk to your lipid specialist at the hospital who helps to manage your cholesterol.

What is LDL-apheresis?

LDL-apheresis is a type of ‘extracorporeal’ (blood taken outside the body) procedure to remove low density lipoprotein (LDL) cholesterol from the blood. LDL-apheresis is considered for those patients who, despite the maximum amount of drug treatment and a cholesterol lowering diet, still have higher LDL cholesterol levels than is healthy.

Many people who require this treatment have a condition called Familial Hypercholesterolaemia, a genetic problem which leads to high LDL cholesterol levels.

Some patients are referred for this treatment because they are unable to tolerate lipid-lowering drugs due to side effects. A few people also require LDL-apheresis because they have slightly raised cholesterol levels and cardiovascular disease which is progressing.

Increased levels of LDL cholesterol increase the risk heart disease as the LDL is deposited in the walls of the arteries causing them to narrow.

LDL-apheresis treatment FAQs
Treatment FAQs

Read our FAQs about LDL-apheresis such as how long is the treatment and how to minimise reactions to the treatment.

LDL - Case studies
Case studies

To be able to read about someone who has LDL apheresis on a regular basis, may help others considering it.

LDL - Find a unit
Find a unit

Use our clickable map to help you locate your nearest Lipid Clinic and Apheresis Unit within the UK.